May 3, 2022 · Inhaled drug formulation involves consideration of multiple factors, including the properties of the API, the needs of the target patient population, the delivery requirements, and the choice of device.

Learn the difference between APIs and formulations in pharma. Explore API drug development, synthesis, and the vital role of CMOs/CDMOs in the industry.

Various wet ball nanomilling-screening tools for poorly soluble APIs are available which differ in their milling principle, batch size and number of samples. Here, the transferability of results from screening (small to. medium-scale) to pharmaceutical production (largescale) was investigated.

The behavior of API crystals in the formulation can be derived from various intrinsic properties like PSD, shape, sur-face roughness, elasticity and can strongly depend on external effects like moisture, electrostatic charging, mode of stress, etc.

Mar 21, 2019 · API form selection is ultimately driven by preformulation, formulation development, drug product manufacturing, and preclinical and early clinical study data.

Understanding and controlling the solid-state properties of your API is a key part of the candidate selection and development journey. Early in development, modest investment in these initial studies and guidance from experienced scientists will help you on your drug development journey.

Jun 27, 2022 · Drug formulation development is a make-or-break moment for new active pharmaceutical ingredients (APIs). During this development phase, an API is combined with excipients, and a dosage form is chosen.

The purpose of this SOP is to provide a detailed procedure for selecting active pharmaceutical ingredients (APIs) during the formulation development process, ensuring the chosen APIs meet project requirements and regulatory standards.

Apr 19, 2025 · Arborpharmchem must distinguish between APIs and formulations to improve therapeutic efficacy in the complex realm of pharmaceutical development. This blog discusses novel active ingredient delivery strategies that handle difficult API …

Nov 13, 2024 · An in-depth understanding of API polymorphism helps formulators select the ideal polymorph for optimal solubility, stability, bioavailability, and manufacturability.