First, we provide unifying definitions of structure and function that can be applied across levels. Second, we consider the degree to which the nature of the structure–function relationship is similar across levels of biological organization.

There are questions involving structure–function relationship without a definitive answer: How can the functional activation patterns be changed? How do plasticity mechanisms become involved? In what way and under what conditions do different favorable plastic responses, neuroprotective and successful from the adaptive point of view, happen ...

Jan 28, 2023 · Here we decompose functional MRI signals from pathological and pharmacologically-induced perturbations of consciousness into distributed patterns of structure-function dependence across...

Jun 20, 2024 · We used multimodal magnetic resonance imaging data from 439 participants aged 5.7–21.9 years to predict functional connectivity by incorporating intracortical and extracortical structural connectivity, characterizing SC–FC coupling.

Aug 16, 2024 · Our findings suggest structure-function correspondence unfolds along a sensory-fugal organizational axis, with higher correspondence in primary sensory and motor cortex for perceptual and...

We provide a systematic analysis of the structure-function relationship in proteins using the novel concept of local descriptors of protein structure. A local descriptor is a small substructure of a protein which includes both short- and long-range interactions.

Jul 2, 2016 · This table is a list of nine structure-function generic patterns that repeat in nature in different systems and scales. We describe these patterns with detailed examples and discuss how to use them in biomimetic design processes.

Jun 1, 2008 · In this review, we reassess the meaning of structural novelty and examine its relevance to the complexity of the structure-function paradigm. Recent advances in the prediction of protein function from structure are discussed, as well as new sequence-based methods for partitioning large, diverse superfamilies into biologically meaningful clusters.

How does the brain’s function emerge from its underlying structure? The relationship between the brain’s anatomy – how bundles of neurons connect disparate regions in complex patterns – to the brain’s function – how those disparate regions coordinate with each other across time to produce cognition, behavior, and states of disease ...

Sequence and structure patterns can be used for characterizing families of proteins which are de”ned to be sets of functionally or structurally related proteins. The discovery of such patterns can help in the understanding of relationships between sequence, structure, and function of proteins and in a bigger