p-Coumaric acid is an organic compound with the formula HOC 6 H 4 CH=CHCO 2 H. It is one of the three isomers of hydroxycinnamic acid. It is a white solid that is only slightly soluble in water but very soluble in ethanol and diethyl ether.

p-Coumaric acid | C9H8O3 | CID 637542 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

p-Coumaric acid was more active than m-coumaric acid (IC 50, 270 μM), o-coumaric acid (IC 50, 300 μM), and other tested compounds, indicating it has an optimized structure to be an effective human tyrosinase inhibitor.

p-Coumaric acid (4-hydroxycinnamic acid) is a phenolic acid that has low toxicity in mice (LD50 = 2850 mg kg(-1) body weight), serves as a precursor of other phenolic compounds, and exists either in free or conjugated form in plants.

Coumalic acid can be synthesized by self-condensation of monomalonaldehyde. There are three types of isomers, o-coumaric acid, m-coumaric acid, and p-coumaric acid, which are distinguished by the position of the hydroxyl substitution of the phenyl group [9].

May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis (PubMed:15563508). It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid (PubMed:15563508)

p-Coumaric acid, trans; Stereoisomers: 2-Propenoic acid, 3-(4-hydroxyphenyl)-, (Z)-

P-Coumaric acid (p-CA) is a hydroxycinnamic acid, an organic compound that is a hydroxyl derivative of cinnamic acid. P-CA is the most abundant isomer in nature and can be found in a wide variety of edible plants such as fungi, peanuts, …

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P-coumaric acid (p-CA), a phenolic acid, is widely distributed in vegetables, fruits and mushrooms. P-CA has demonstrated a protective role against oxidative stress and inflammation in various diseases, including cardiovascular disease, diabetes and cancer.