25I-NBOMe (2C-I-NBOMe, Cimbi-5, and also shortened to " 25I "), also known as Smiles, or N-Bomb, is a novel synthetic psychoactive substance with strong hallucinogenic properties, synthesized in 2003 for research purposes. Since 2010, it has circulated in the recreational drug scene, often misrepresented as LSD.

Jul 12, 2023 · NBOMe (N-bombs) are a class of psychedelic drugs within the greater phenethylamine family. There are dozens of different NBOMe compounds in this group, but the most common, by far, is a chemical called 25I-N-BOMe. These compounds work through the same mechanisms as LSD, DMT, psilocybin, and mescaline.

N-BOMe, commonly referred to as “N-bomb” or “Smiles,” is a powerful synthetic hallucinogen sold as an alternative to LSD or mescaline (a hallucinogenic drug made from a cactus plant).

25B-NBOMe (NBOMe-2C-B, Cimbi-36, Nova, BOM 2-CB) is a derivative of the phenethylamine psychedelic 2C-B, discovered in 2004 by Ralf Heim at the Free University of Berlin.

We report two cases of NBOMe intoxication in patients who believed they used 25I-NBOME, while lab confirmation proved otherwise. Whether unique clinical manifestations are specific to the NBOMe variant, dose, route of administration, or other factors is unknown.

NBOMe is a synthetic hallucinogen that is classified as a New Psychoactive Substance (NPS). It is an extremely powerful drug that is designed to mimic the effects of drugs like LSD, mescaline, and methamphetamine.

NBOMe compounds are ultrapotent and highly efficacious agonists of serotonin 5-HT 2A and 5-HT 2C receptors (Ki values in low nanomolar range) with more than 1000-fold selectivity for 5-HT 2A compared with 5-HT 1A.

Conclusions: Currently, there is evidence suggesting limited use of the NBOMe class of drugs as novel psychoactive substances compared with that of classical recreational drugs and other novel psychoactive substances such as mephedrone. Keywords: Acute toxicity; NBOMe; Novel psychoactive substances; Recreational drugs.

NBOMes (N-methoxybenzyl) are a group of psychedelic drugs. which means they can affect all the senses, altering a person’s thinking, sense of time and emotions. Psychedelics can cause a person to hallucinate, seeing or hearing things that do not exist or are distorted. 1. There are a number of different NBOMes, including 25B-NBOMe and 25C-NBOMe.

Mar 1, 2019 · NBOMes are a new class of potent hallucinogens widely present in illicit drugs. Little is known about this class of drugs, regarding its detection and clinical manifestations of intoxication. This study aims to enhance care involving NBOMes by reviewing the literature on their clinical manifestations and laboratorydetection.