NAG depletion did not substantially affect Golgi morphology and protein export from the ER, but it caused redistribution of Golgi recycling proteins accompanied by a defect in protein glycosylation. These results together suggest that NAG links between p31 and ZW10-RINT-1 and is involved in Golgi-to-ER transport.

The Golgi apparatus (/ ˈ ɡ ɒ l dʒ i /), also known as the Golgi complex, Golgi body, or simply the Golgi, is an organelle found in most eukaryotic cells. [1] Part of the endomembrane system in the cytoplasm, it packages proteins into membrane-bound vesicles inside the cell before the vesicles are sent to their destination.

Feb 11, 2025 · Golgi apparatus, organelle of eukaryotic cells that is responsible for transporting, modifying, and packaging proteins and lipids. The Golgi apparatus is made up of a series of flattened, stacked pouches called cisternae and is located in the cytoplasm near the cell nucleus.

Nov 23, 2024 · The Golgi apparatus, also known as the Golgi complex, Golgi body, or simply Golgi, is a vital organelle in eukaryotic cells. It plays a central role in modifying, sorting, and packaging macromolecules for transport to their destinations.

Golgi apparatus was one of the first organelles observed and described by early light microscopists due to its highly visible structure resembling that of pancakes. Golgi stacks consist of four to six cisternae; however, certain unicellular flagellates may contain up to 60.

Jun 17, 2019 · Also known as the Golgi complex or Golgi body, the Golgi apparatus is an organelle in eukaryotic organisms that moves molecules from the endoplasmic reticulum to their destination, and also modifies products of the endoplasmic reticulum to their final form.

The Golgi apparatus, or Golgi complex, functions as a factory in which proteins received from the ER are further processed and sorted for transport to their eventual destinations: lysosomes, the plasma membrane, or secretion.

Here we review the major discoveries in the mechanisms of Golgi structure formation, regulation, and alteration in relation to its functions in physiological and pathological conditions to further our understanding of Golgi structure and function in health and diseases.

Depletion of NAG Changes the Distribution of Recycling Proteins without Substantially Affecting Golgi Morphology. To reveal the role of NAG in the early secretory pathway, we first examined the distribution of proteins in the Golgi and the ER-Golgi interface in …

Mar 15, 2019 · The Golgi apparatus or Golgi body is often called the cell's packing plant or post office. This organelle modifies, packs and transports important molecules, such as proteins and lipids. The Golgi apparatus is adjacent to the endoplasmic reticulum and is found only in eukaryotic cells.