Feb 21, 2017 · Here, we report that analyses of genes coordinately upregulated with IL-6 pointed to STAT4 and leukemia inhibitory factor (LIF) as potentially linked. Gene silencing revealed …

Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene. [5] In addition, osteoblasts …

Leukemia inhibitory factor (LIF) is the most pleiotropic member of the interleukin-6 family of cytokines. It utilises a receptor that consists of the LIF receptor β and gp130 and this receptor …

Autocrine LIF is required for IL-6 regulation. LIFR has been shown to bind several IL-6 family ligands including cardiotrophin-1 (CTF-1), ciliary neurotrophic factor (CNTF) and leukemia …

Leukemia Inhibitory Factor (LIF) is a member of the Interleukin 6 (IL-6) cytokine family [1]. The LIF receptor forms a heterodimer with gp130 upon LIF binding, which activates tyrosine kinase …

Leukemia inhibitory factor (LIF) is a member of the IL-6 cytokine family, which also includes IL-6, IL-11, IL-27 p28/IL-30, IL-31, Oncostatin M (OSM), Cardiotrophin-like cytokine (CLC), Ciliary …

Sep 25, 2018 · In this Review, we draw on recent advances to provide a timely update on the biology of IL-6 family cytokines and their clinical potential as therapeutic targets or disease …

Nov 19, 1997 · CT-1 also has recently been found to be a member of the IL-6 cytokine family and to be capable of causing myocardial hypertrophy. 10 11 These findings suggested that gp130 …

The interleukin (IL)-6 family cytokines is a group of cytokines consisting of IL-6, IL-11, ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), oncostatin M (OSM), cardiotrophin …

Feb 21, 2017 · Here, we report that analyses of genes coordinately upregulated with IL-6 pointed to STAT4 and leukemia inhibitory factor (LIF) as potentially linked. Gene silencing revealed …