Gain-of-function experiments are ingrained in the scientific process. In many instances, the benefits that stem from gain-of-function experiments are not immediately clear. Only decades later does the ...

Freezing of gait (FOG) is an episodic gait disturbance affecting locomotion in Parkinson's disease. As a biomarker to detect FOG, the Freeze index (FI), which is defined as the ratio of the areas ...