Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson's disease in mice.

Metabolic dysfunction-associated steatohepatitis (MASH) significantly increases the risk of liver cirrhosis and ...

Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical ...

Most mutations that decreased antibiotic susceptibility were related to specific metabolic pathways. A MIC-increase to ...

Mitochondrial stress disrupts insulin production in diabetes, but reversing the damage may restore β-cell function.

A multi-omics study reveals that impaired branched-chain amino acid (BCAA) catabolism is a key driver of sarcopenia, ...

Results: The MetaboLINK analysis of longitudinal metabolomics data has revealed distinct pathways related to amino acids, lipids, and energy metabolism ... CD24 for EBs, ZO-1 for Rosettes, Nestin for ...

Roche has secured a new FDA approval for its first companion diagnostic test aimed at identifying breast cancer patients with so-called “HER2-ultralow” status. The company’s PATHWAY HER2 ...

First the study will evaluate the linkages between carbohydrate intake and obesity, potentially stratified by metabolic syndrome status ... with the attributability of carbohydrate intake in part 1 to ...

An improved understanding of the metabolic pathways dysregulated in CLE may lead to novel treatment ... especially CLE, is less well-studied.1 The objective of this study was to perform an unbiased ...

Basel, 31 January 2025 - Roche (SIX ... tissue samples. The PATHWAY HER2 (4B5) test was used as part of the DESTINY-Breast06 trial, which showed a median progression-free survival of 13.2 months with ...

(PRESS RELEASE) BASEL, 1-Feb-2025 — /EuropaWire/ — Roche (SIX: RO, ROG; OTCQX: RHHBY) has announced that the U.S. Food and Drug Administration (FDA) has granted an expanded label for its PATHWAY® anti ...