Eli Lilly & Co. and Evotec International GmbH have disclosed Rho-associated protein kinase 2 (ROCK2) inhibitors reported to be useful for the treatment of cancer, autoimmune disease, fibrosis, and ...

This CME program explores the medical management of glaucoma using Rho kinase inhibitors (ROCKis) to lower intraocular pressure (IOP) and reduce episcleral venous pressure.

ROCK2 inhibitors affect Rho kinase pathways, which regulate the movement of cells and the production of pro-inflammatory chemicals called cytokines.

Transforming Glaucoma Care With Rho Kinase Inhibitors This activity is supported by an educational grant from Alcon Vision, LLC.

Key Takeaways Descemet stripping only (DSO) offers a novel approach to FECD management, avoiding donor tissue complications and promoting endothelial restoration. Rho kinase inhibitors, such as ...

They received one of three doses of the regenerative medicine—which comprises allogeneic human corneal endothelial cells and a rho kinase inhibitor—or the rho kinase inhibitor alone or the ...

An important component of cellular mechanotransduction is the enzyme Rho kinase (ROCK). A study by Martino et al. 9 showed that mechanical signal propagation and processing can be controlled via ...

It works by affecting Rho kinase pathways, which are involved in cellular mobility and the production of pro-inflammatory substances called cytokines.

Rho kinase inhibitors Rho kinase inhibitors are another eye drop that helps increase the drainage of intraocular fluid. They work by improving the outflow of the trabecular meshwork.

Heart failure with preserved ejection fraction (HFpEF) observed in women with estrogen depletion is a consequence of the reduction of cardioprotection and endothelial dysfunction. Rho-kinase (ROCK) ...