Messier 57, better known as the Ring Nebula, is the glowing remains of a sun-like star. It is 2,000 light-years away from the Earth. This stunning image of Ring Nebula was captured by James Webb ...

BACKGROUND: Morbidity and mortality of heart failure with preserved ejection fraction (HFpEF) is increased in metabolic disorders. However, options for preventing and treating these prevalent outcomes ...

It is about 35 million light-years away in the southern constellation Reticulum. Credit: Space.com | ESA/Webb, NASA & CSA, A.

The Ca2+ stored in the cellular endoplasmic reticulum (ER) plays a crucial role in protein folding and lipid transfer, and its impairment leads to cellular ER stress. When chronic cellular ER stress ...

Throwing new light into this domain, the NCBS scientists have proposed that Esyt possesses a C2 domain capable of binding and ...

newcastle.edu.au Introduction The significance of endoplasmic reticulum (ER) stress in asthma is unclear. Here, we demonstrate that ER stress and the unfolded protein response (UPR) are related to ...

Imbalances in endoplasmic reticulum function and mitochondrial quality control are important potential drivers of inflammation and oxidative stress. In addition, many studies have confirmed the ...

Endoplasmic reticulum stress (ERS) is the removal of unfolded and misfolded proteins and is an important mechanism for the maintenance of cellular homeostasis. ERS plays an important role in the ...

The metazoan endoplasmic reticulum (ER) serves both as a hub for maturation of secreted proteins and as an intracellular calcium storage compartment, facilitating calcium-release-dependent cellular ...