Expert Rev Ophthalmol. 2013;8(6):527-537. Protein kinase C-mediated contraction of RPE cells is stopped by an anti-PDGF antibody. Unfortunately, blocking PDGF is ineffective at suppressing PVR in ...
The battle over the Jio Hotstar domain has taken an unexpected turn, with the website now acquired by two Dubai-based siblings, Jainam and Jivika, days after its original owner—a Delhi-based anonymous ...
Domain Group is a leading Australian property marketplace made-up of a portfolio of brands. We are united in our Purpose to inspire confidence in life’s property decisions. Our brands offer ...
Our drug discovery model has identified two novel STAT3 SH2 domain inhibitors 323–1 and 323–2 (delavatine A stereoisomers) in a series of experiments. In silico computational modeling, drug affinity ...
Besides, TCPTP is capable of regulating diverse signaling pathways by dephosphorylating various RTKs (e.g., IR, EGFR, VEGFR, PDGFR, and CSF-1R). TCPTP, T cell protein tyrosine phosphatase; IL-6, ...
Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination
Platelet-derived growth factor (PDGF) is critical for steady-state number and differentiation of oligodendrocyte precursor cells (OPCs), but its downstream targets are unclear. Here, we show for the ...
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