Expert Rev Ophthalmol. 2013;8(6):527-537. Protein kinase C-mediated contraction of RPE cells is stopped by an anti-PDGF antibody. Unfortunately, blocking PDGF is ineffective at suppressing PVR in ...
PDGF isoforms bind to the related PDGFRs ... 4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA), gene fusions involving ETS variant transcription factor 6 (ETV6)-neurotrophic tyrosine receptor ...
Investopedia / Mira Norian Generation Alpha is the name given to those born between 2010 and 2024. Generation Alpha is the first generation born entirely in the 21st century, between 2010 and 2024.
Besides, TCPTP is capable of regulating diverse signaling pathways by dephosphorylating various RTKs (e.g., IR, EGFR, VEGFR, PDGFR, and CSF-1R). TCPTP, T cell protein tyrosine phosphatase; IL-6, ...
Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination
Platelet-derived growth factor (PDGF) is critical for steady-state number and differentiation of oligodendrocyte precursor cells (OPCs), but its downstream targets are unclear. Here, we show for the ...
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