Expert Rev Ophthalmol. 2013;8(6):527-537. Protein kinase C-mediated contraction of RPE cells is stopped by an anti-PDGF antibody. Unfortunately, blocking PDGF is ineffective at suppressing PVR in ...
Figure 2 PDGF/PDGFRA signaling pathways and agent treatments. In PDGFRA mutaled GIST. PDGF isoforms bind to the related PDGFRs, initiate distinct receptor dimerization and phosphorylation, thereby ...
To investigate whether AS1517499 affects myeloid fibroblasts accumulation, kidney sections were stained for the hematopoietic marker CD45 and mesenchymal marker PDGFR-β. The number of CD45 and PDGFR-β ...
Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination
Platelet-derived growth factor (PDGF) is critical for steady-state number and differentiation of oligodendrocyte precursor cells (OPCs), but its downstream targets are unclear. Here, we show for the ...
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