Expert Rev Ophthalmol. 2013;8(6):527-537. Protein kinase C-mediated contraction of RPE cells is stopped by an anti-PDGF antibody. Unfortunately, blocking PDGF is ineffective at suppressing PVR in ...
Jak Roberto is beaming with excitement as his new home is almost complete, although he admitted that the construction did not come without challenges. The actor featured some parts of his three ...
The biotechnology sector has experienced unprecedented growth and innovation in recent years. As we look at the landscape in 2025, it’s clear that biotech has become an integral part of the global ...
In PDGFRA mutaled GIST. PDGF isoforms bind to the related PDGFRs, initiate distinct receptor dimerization and phosphorylation, thereby activating various signaling pathways including the RAS-MEK-MAPK, ...
Jak Alnwick signed a new contract last month, keeping him at Cardiff until 2026 Cardiff City are set to be without Jak Alnwick for the rest of the season after the goalkeeper tore his hamstring ...
The levels of Flt-3 L, IL-3, IL-33, MIP-1α, PD-L1, CD40 L, G-CSF, TRAIL, PDGF-AB/BB, TGF-α, and VEGF were significantly higher in CRVO than in BRVO. KEGG pathway enrichment revealed that these ...
Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination
Platelet-derived growth factor (PDGF) is critical for steady-state number and differentiation of oligodendrocyte precursor cells (OPCs), but its downstream targets are unclear. Here, we show for the ...
Direct activation of the human phospholipase C-γ isozymes (PLC-γ1, -γ2) by tyrosine phosphorylation is fundamental to the control of diverse biological processes, including chemotaxis, platelet ...
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