Primary biliary cirrhosis (PBC) is a chronic, cholestatic liver disease characterized by progressive destruction of intrahepatic bile ducts, resulting in chronic cholestasis, portal inflammation ...

I wasn't ill apart from some tiredness.” After being on the organ donor waiting list for four months, Mandy was matched with ...

Too much bile in the body can lead to inflammation and damage to the liver. Livdelzi is usually taken together with another medicine for PBC called ursodeoxycholic acid (also called ursodiol or urso).

At the start of the year, there had been no new therapies for rare cholestatic liver disease primary biliary cholangitis (PBC) in the US for almost a decade. With the FDA approval of Gilead's ...

Our study aimed to determine whether etiological treatments in PBC-specific antibody-positive patients could improve liver biochemical tests, thereby distinguishing them from individuals with PBC.

GSK has reported promising results with a drug to treat the severe itching that plagues patients with rare cholestatic liver disease primary biliary cholangitis (PBC). Interim results from the ...

“This designation follows our presentation of positive topline data from the Phase 2a clinical trial of CNP-104 in PBC at The Liver Meeting® 2024. Notably, in addition to demonstrating ...

Gilead Sciences’ Livdelzi (seladelpar) has been approved by the Medicines and Healthcare products Regulatory Agency (MHRA) to treat adults with the rare liver disease primary biliary cholangitis (PBC) ...

And there was.” Mandy, from Newcastle-under-Lyme in Staffordshire, was diagnosed with primary biliary cholangitis (PBC), a liver disease which causes liver failure. The condition also leaves ...