RNA localization and localized translation are especially relevant in polarized cells like neurons where neurites extend dozens to hundreds of centimeters away from the soma. Local translation confers ...

The Ca 2+-dependent activator protein for secretion (CAPS/CADPS) family protein facilitates catecholamine release through the dense-core vesicle exocytosis in model neuroendocrine cell lines. However, ...

The human neurons grew multiple neurites, or wiry projections that help the nerve cells send and receive signals. But the chimp neurons only grew single neurites. When human HARs were engineered into ...

Artificially-derived chimpanzee neurons grow only one or two neurites (connecting wires), as shown in the center image. Human-accelerated regions (HARs) in chromosomes help human neurons grow multiple ...

During the peer-review process the editor and reviewers write an eLife assessment that summarises the significance of the findings reported in the article (on a scale ranging from landmark to useful) ...

It is also well known that neurons initially extend an excess number of neurites most of which will later be eliminated by the mechanism called neurite pruning (Riccomagno and Kolodkin, 2015; ...