Anti-C1q antibodies are highly prevalent among patients with IgG4-RD, particularly those with renal and skin manifestations.

To assess treatment toxicity, mice were weighed weekly. Renal pathology was assessed by scoring for glomerulonephritis (GN), glomerulosclerosis (GS), and interstitial nephritis (IN) on a 0–4 scale, ...

The FDA has granted Fast Track designation to ADI-001 for the treatment of refractory systemic lupus erythematosus with extrarenal involvement.

A study showed notable differences in bone mineral density between children on steroids and those not on steroids, with 84% ...

Obinutuzumab, a humanized type II anti-CD20 monoclonal antibody, provided significantly better renal responses than placebo in a phase 2 trial involving patients with lupus nephritis receiving ...

Expert Rev of Obstet Gynecol. 2012;7(3):269-279. In summary, excess levels of urobilinogen and bilirubin in the urine may signal liver disease, and more research is needed to correlate these ...

CYC and rituximab should be considered in organ-threatening and refractory disease, respectively. For active lupus nephritis, GC, mycophenolate or low-dose intravenous CYC are recommended as anchor ...

The treatment procedures are required in the case of the severity of the condition. The patient then needs to go for a kidney ...