Background Restarting direct oral anticoagulants (DOACs) after a serious bleeding event in patients with atrial fibrillation ...

Objectives Cardiopulmonary involvement (CPI) is a major cause of morbidity and mortality in systemic sclerosis (SSc). The 6 min walk test (6MWT) is widely used to assess functional capacity, but its ...

Proper handling of continuous variables is crucial in healthcare research, for example, within regression modelling for descriptive, explanatory, or predictive purposes. However, inadequate methods ...

Dr. James McCaffrey presents a complete end-to-end demonstration of the kernel ridge regression technique to predict a single numeric value. The demo uses stochastic gradient descent, one of two ...

"Rather than waiting for data integrations or struggling to interpret ad hoc reports, teams know where to focus, how to deploy resources, and what results to expect," its president says.

Survival models using electronic health record data show promise in predicting progression to proliferative diabetic ...

Surgery is a mainstay treatment for head and neck squamous cell carcinoma (HNSCC). However, the clinical challenge is to ...

The R package rcssci offers an intuitive solution for visualizing Restricted Cubic Splines (RCS) in regression analyses. It automates the generation of spline plots for outcomes like odds ratios (OR), ...

The bias of kernel methods based on local constant fits can have an adverse effect when the derivative of the marginal density or that of the regression function is large. The drawback can be repaired ...

Neuroscientists have taken a major step toward detecting Alzheimer’s disease in its earliest stages—long before memory loss ...