This Perspective provides an overview of the major advances in recent years in the computational design and structure prediction of α-helical membrane proteins. The computational design of α ...

Design levels describe the same structure, but in different terms. For instance, a machine may perform on an architectural level a fixed-point addition (a+b)-radix n. An end-user may describe this ...

In a preprint posted on bioRxiv, Profluent introduces a new method which now incorporates structural and functional context to protein language models for conditioned design. The approach, termed ...