Cardiovascular diseases are one of the leading causes of death and global health problems worldwide. Multiple factors are known to affect the cardiovascular system from lifestyles, genes, underlying ...

Each of our trillions of cells bustles with activity in a carefully choreographed quest to keep us healthy. At their core, quality control mechanisms ensure that the right proteins are in the right ...

Figure 1. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) M pro cleavage sites in selected target proteins. The proteins are depicted along with the corresponding PDB ID, except for FAF1, ...

Phosphoinositides (PI) are key regulators of cellular organization in eukaryotes and genes that tune PI signaling are implicated in human disease mechanisms. Biochemical analyses and studies in ...