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However, CXCL12 expression is indispensable for HSC homing to neonatal bone marrow (Ara et al., 2003), and most HSCs are cycling at neonatal stage. It is possible that the structure of neonatal bone ...

A comprehensive understanding of in vivo heterogeneity and specificity of HSC responses to external stimuli is currently lacking. We performed single-cell RNA sequencing (scRNA-Seq) on functionally ...

Similar to other blood cells, NK cells are generated from hematopoietic stem cells (HSC) residing in the bone marrow. Following the first experimental evidence of the possibility to rescue mice from ...

A hallmark of adult hematopoiesis is the continuous replacement of blood cells with limited lifespans. While active hematopoietic stem cell (HSC) contribution to multilineage hematopoiesis is the ...