This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...

Specifically, Auletta highlights the emerging science in stem cell transplants and cell therapies, including treatments like chimeric antigen receptor (CAR) T-cell therapy. He also discussed topics ...

This indicates that GLP-1 receptor agonists lead to greater reduction in overall body fat than that in muscle mass, resulting in an overall body fat percentage decrease of around 4.5%.

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Testosterone helps release growth hormones, which stimulate tissue growth, and it connects with nuclear receptors in DNA, which causes protein synthesis (or muscle growth). Turner points out that ...

Here we showed that genetic ablation of FGF signaling prevented lens induction by disrupting transcriptional regulation and actin cytoskeletal arrangements, which could be reproduced by deleting the ...

In a surprising discovery, scientists have found that the heart possesses 'sweet taste' receptors, similar to those on our tongues, and that stimulating these receptors with sweet substances can ...

Additionally, their research may explain why high consumption of artificially sweetened beverages is linked to arrhythmogenesis, or an irregular heartbeat. Not only are these sweet taste receptors ...

2015). Receptor tyrosine kinases (RTKs), such as IGFR1, VEGFR, EGFR, FGFR4, and PDGFRα become constitutively activated and cause downstream tumorigenic effects in the presence of PAX-FOXO1 gene ...

Ephrin type-B receptor 4 (EphB4) is a tyrosine kinase-type receptor that ... and ultimately favors a migratory and metastatic phenotype. Although measures of FGFR4 levels in CRC through IHC remains ...