The authors have generated important resources such as a reference dataset of early primate development by utilizing single-cell transcriptomic technology together with induced pluripotent stem cells ...

Umut A. Gurkan is leading the CASE Biomanufacturing and Microfabrication Laboratory (CASE-BML). Dr. Gurkan’s research is focused on microcirculation, vascular biology, red blood cells, hemoglobin, ...

Now, Harvard scientists who pioneered some of the advances that allow for the creation of what they’ve dubbed synthetic human entities with embryo-like features (SHEEFs), are calling for a rethink of ...

For several years, researchers studied human embryonic stem cells (ESCs) to understand the unique features of these pluripotent cells, but on their own, they poorly resembled the complex structures ...

Embryonic stem cell cultures are thought to self-organize into embryoid bodies, able to undergo symmetry-breaking, germ layer specification and even morphogenesis. Yet, it is unclear how to reconcile ...