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The image on the laptop screen shows the 3D structure of a large protein-free RNA complex — one of three unprecedented structures their research collaboration discovered using cryo-EM at SLAC.
Other proteins modulate the formation of alternative structures, such as Z-DNA and G-quadruplexes, that are important in reloading the RNA polymerase enzymes after each transcription cycle.
Nucleic acids, such as DNA and RNA, serve as direct inputs by leveraging complementary substrate designs, allowing applications in transcriptome analysis and live-cell monitoring.
They called these dots “herasomes,” and inside them were amyloid-like structures that are known to have the DNA-like ability to replicate themselves, making them possible inheritance vectors.
NASA scientists found amino acids, key minerals, and nucleobases for DNA in samples from the OSIRIS-REx asteroid mission. It's a win for alien life.
DNA and RNA methylation, initially thought to operate as distinct pathways, have been shown to interact closely, shifting our understanding of gene regulation. A team of researchers from the ...
A deeper understanding of RNA’s role in DNA repair could lead to new strategies for strengthening repair mechanisms in healthy cells, potentially reducing the harmful effects of treatments like ...
The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team.
The next generation of genome editing is making big changes to DNA Using bridge RNA, scientists can induce large insertions, deletions, and rearrangements in a genome by Max Barnhart ...
For instance, only a few years after Francis Crick, James Watson and several of their colleagues deduced the structure of DNA, researchers found that some RNA, called transfer RNA, grabs onto ...
Google DeepMind launches AlphaFold 3, the next generation of its molecular structure prediction model that can aid drug discovery and other molecular developments.
Google DeepMind expands its AlphaFold AI system to model how proteins interact with other cell structures including DNA and RNA.
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