The management of breast cancer involves various therapeutic approaches. However, many current anticancer treatments indiscriminately damage both cancerous and healthy cells. In cancer treatment, ...

Researchers have shed new light on how tissues in the body are repaired following the damage and premature death of tissue ...

The FDA has granted orphan drug designation to PEP-010 for pancreatic cancer, advancing its development as a potential novel ...

College of Chemistry, Jilin Province Research Center for Engineering and Technology of Spectral Analytical Instruments, Jilin University, Qianjin Street 2699, Changchun 130012, China School of ...

The extract worked wonders by up-regulating pro-apoptotic proteins (Caspase 3, Caspase 9, and P53) while down-regulating BcL2, a key protein that helps cancer cells survive. “Molecular docking ...

SpaceX is reviewing data from the recent incidents to improve the reliability of future Falcon 9 flights. (Updates with the latest information) SpaceX's Falcon 9 rocket is upright on its Kennedy ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Influenza A virus (IAV) Matrix 2 protein (M2) ...

This manuscript reports fundamental discoveries on how necrotic cells contribute to organ regeneration through apoptotic signalling to produce cells with non-lethal apoptotic caspase activity that ...

Besides, increased AIM2 expression was accompanied by activation of the pyroptosis pathway (cleaved-caspase-1, GSDMD-FL, GSDMD-NT) in the renal cortex of db/db mice and HG-induced HK2 cells in vitro.

Binding of bacterial LPS to its cytosolic sensor, caspase-11 (Casp11), promotes Casp11 aggregation within a high-molecular-weight complex known as the noncanonical inflammasome, where it is activated ...