New research from Professor Guillermo Ameer’s team shows how a shape change of a cell’s nucleus can trigger regenerative ...

ABSTRACT Osteoinductivity of demineralized bone matrix has been attributed to bone morphogenetic proteins (BMP). Other growth factors, including insulin-like growth factor-I (IGF-I) and ...

The research, conducted with the aim of improving early management and surgical outcomes for bone infections, focused on modifying demineralized bone matrix (DBM), a naturally derived material ...

Demineralized bone matrix assists in managing these disorders by promoting bone regeneration and healing, reinforcing recovery by providing an osteoinductive scaffold that supports natural bone ...

Estroff led the necessary materials synthesis and characterization techniques of the different bone matrix models, which the team then used to investigate tumor cell behavior, first in vitro and then ...

Around 500 million years ago, early vertebrates in the seas became fish, adopting an inner skeleton and a flexible spine based on a nanocomposite of fibers and mineral, known as bone material ...

Our results tend to support these overall findings of reliable remodelling of DBM to new bone. The histological analysis showed significant new bone formation and decreasing residual DBM material ...

In this matrix, made of a soft hydrogel, the cells (osteoblasts) that form bone can settle, multiply and connect with each other and their offshoots to form a three-dimensional network.

In a 2021 study, Beloti's group demonstrated that osteoblasts produce the agrin protein. Osteoblasts are cells responsible for forming the mineralized matrix of bone tissue. The researchers then ...

A new study by Rice University researchers indicates that bioengineers growing bone in the laboratory may be able to create the mechanical stimulation needed to grow bone outside the body.

This article presents a histological analysis of demineralised bone matrix and its effectiveness in enhancing posterior fusion of the spine.

A connection between reduced bone health and the behavior of tumor cells is well-established. For example, decreased bone-mineral density has been correlated with increased risk for metastasis, and ...