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This is routinely achieved by placing the paraffin blocks on ice, cooling both the tissue and the wax to a similar consistency and swelling the tissue to make it easier to section. As the block heats ...
The backbone of daily pathological diagnostic work is the paraffin section. Paraffin sections are still prepared by methods largely unchanged for over 150 years. A xylene-free method has been ...
An invaluable source of RNA, DNA, and chromatin from historical and clinical samples is formalin fixed paraffin embedded (FFPE) tissue. Globally, tissue banks, hospitals, and laboratories are ...
Paraffin wax continues to be the most popular embedding medium, due to its low cost and ease of use, facilitating long-term storage of the embedded tissue blocks.