1 Under the conditions of their experiments they demonstrated that the renal tubules must make an ... ions and concomitant diminution of sodium reabsorption. It was of some interest that the ...

It is believed that the water metabolism of the kidney is related to the ball-tube balance. The colloid osmotic pressure in peritubular capillaries can regulate the reabsorption of sodium and water in ...

NSAIDs inhibit the synthesis of renal prostaglandin, which results in a higher total blood volume, cardiac output and preload. The association between recent start of NSAIDs in elderly people and ...

This important study addresses the idea that defective lysosomal clearance might be causal to renal dysfunction in cystinosis. With mostly solid data, the authors observe that restoring expression of ...

SGLT2 inhibitors (red text) block the reabsorption of Na+ and glucose in the proximal ... SGLT2 inhibitors were developed to block the co-transport of sodium and glucose in the renal tubule to ...

A Phase 3 clinical trial found that injections of the semaglutide medication once weekly reduced the risk of kidney disease worsening by 24% in people who also had diabetes. It also reduced the ...

Renal tubular phosphate reabsorption increased from the baseline in both groups. In both groups, the mean serum alkaline phosphatase level decreased. The patients’ physical abilities improved, and ...

15 Renin–angiotensin–aldosterone inhibitors can increase serum creatinine due to renal afferent arteriole vasodilation; however, relatively small increases soon after initiation predict long-term ...

In proximal tubule cells and enterocytes, type II sodium–phosphate cotransporters ... is the primary regulator of phosphate reabsorption in kidney. Hormonal (PTH and atrial natriuretic peptide ...

The developmental mechanisms underlying P-D axis patterning in epithelial tubules are not well understood for any organ. The insect renal (or Malpighian) tubule is a relatively simple epithelial ...