It can result from underlying conditions, such as kidney failure, or other factors, including drinking too much water or taking certain medications. Health experts define a low sodium level in the ...

FIGURE 2. Overview of kidney cell types. Abbreviations: PCT, proximal convoluted tubule; PST, Proximal straight tubule; DTL, descending thin limb of loop of Henle; ATL, ascending thin limb of loop of ...

This important study addresses the idea that defective lysosomal clearance might be causal to renal dysfunction in cystinosis. With mostly solid data, the authors observe that restoring expression of ...

SGLT2 inhibitors (red text) block the reabsorption of Na+ and glucose in the proximal ... SGLT2 inhibitors were developed to block the co-transport of sodium and glucose in the renal tubule to ...

A Phase 3 clinical trial found that injections of the semaglutide medication once weekly reduced the risk of kidney disease worsening by 24% in people who also had diabetes. It also reduced the ...