Randomized controlled trials are the most reliable method available for testing new treatments. They have become the standard that pharmaceutical companies must meet for calculating and proving ...

Our aim was to examine the strength of this association through a detailed meta-analysis and meta-regression analysis of randomized controlled trials (RCTs). Methods A comprehensive search for trials ...

Although the results of observational research and pragmatic trials can complement those of classic randomized, controlled trials, they must be interpreted carefully. 1,3,7 In particular, the very ...

Fabricatore, AN, Wadden, TA, Moore, RH, et al. Attrition from randomized controlled trials of pharmacological weight loss agents: a systematic review and analysis. Obes Rev 2009;10:333-341 Crossref ...

David C. Mohr, Bonnie Spring, Kenneth E. Freedland, Victoria Beckner, Patricia Arean, Steven D. Hollon, Judith Ockene, Robert Kaplan, The Selection and Design of Control Conditions for Randomized ...

PRODIGE 35 is a randomized phase II trial that evaluated three first-line schedules of chemotherapy in mPC: FOLFIRINOX until ... Maintenance treatment with capecitabine and bevacizumab in metastatic ...

RCTs, cluster-randomised trials and randomised cross-over studies were included if they compared an exercise therapy intervention with a non-exercising control treatment. Types of participants Studies ...

Jaeb Center for Health Research conducted a randomized controlled trial evaluating the impact of automated insulin delivery (AID) in adults with insulin-treated type 2 diabetes. AID significantly ...