In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be ...

A predictive biophysical model that integrates protein-DNA structures and sequences to accurately determine genomic binding sites and affinities of DNA-binding proteins.

Inside each cell of the human body are proteins that control which genes are expressed at the right place and time. However, ...

Unlike structure-based models, which are limited to a small set of resolved protein-ligand complexes, ProtoBind-Diff leverages a larger pool of chemical and biological data, which helps the model ...

Lawrence Livermore National Laboratory (LLNL) researchers have developed a novel 3D printing technique that uses light to build complex structures, then cleanly dissolves the support material ...

As summer kicks into full gear and people are spending more time outside, there's one thing on many people's minds - ticks.

Abstract Summary Pharmacological enhancement of endoplasmic reticulum (ER) proteostasis is an attractive strategy to mitigate pathology linked to etiologically-diverse protein misfolding diseases.

A newly created cell model of the amniotic sac could reveal new insights into early pregnancy, as well as generate helpful ...