Expert Rev Ophthalmol. 2013;8(6):527-537. Protein kinase C-mediated contraction of RPE cells is stopped by an anti-PDGF antibody. Unfortunately, blocking PDGF is ineffective at suppressing PVR in ...

Jesy Nelson has opened up about the complications she is experiencing during her pregnancy in a heartfelt new Instagram video. The former Little Mix singer, 34, alongside her partner Zion Foster ...

Heat-shock protein 90 (Hsp90) inhibitor downregulates c-Myc expression and upregulates the expression of tumor repressor proteins such as p53 and pRB, inhibiting the G1/S transition and causing G2 ...

Figure 2 PDGF/PDGFRA signaling pathways and agent treatments. In PDGFRA mutaled GIST. PDGF isoforms bind to the related PDGFRs, initiate distinct receptor dimerization and phosphorylation, thereby ...

In spite of the widespread role of calmodulin (CaM) in cellular signaling, CaM mutations lead specifically to cardiac manifestations, characterized by remarkable electrical instability and a high ...

Lipoic acid (LA) dose-dependently protects bone losses in the mandible of rats during the development of osteopenia by inhibiting oxidative stress and promoting bone formation.