Munich news, health insurance, technology, jobs and other topics for expatriates. The Eye Newspapers covers daily news and offers services for foreigners.

The over-activated CAFs secrete pro-tumor growth factors such as vascular endothelial growth factor VEGF and PDGF as well as extracellular matrix components, which promote the growth and invasion of ...

Pediatric high-grade gliomas, particularly H3K27M diffuse midline gliomas (DMG), are aggressive malignant brain tumors with a poor prognosis. Previous research suggests that platelet-derived ...

Malignant gliomas and medulloblastomas — the most common brain tumours affecting adults and children, respectively — remain responsible for a disproportionate level of morbidity and mortality ...

The glioma tumors from 17 individuals (with an average fire-fighting history of 22 years) were compared with those from 18 individuals in non-firefighting occupations.

Expert Rev Ophthalmol. 2013;8(6):527-537. Protein kinase C-mediated contraction of RPE cells is stopped by an anti-PDGF antibody. Unfortunately, blocking PDGF is ineffective at suppressing PVR in ...

The study is funded with a California Institute for Regenerative Medicine (CIRM) grant to advance the development of DB107 in patients with newly diagnosed high-grade glioma. Led by Noriyuki ...

Mar. 13, 2025 — A study shows that high-grade glioma tumor cells harboring DNA alterations in the gene PDGFRA responded to the drug avapritinib, which is already approved by the United States ...

Centre for 3D models of Health and Disease, Division of Surgery and Interventional Science, University College London, London W1W 7TY, U.K. Centre for 3D models of Health and Disease, Division of ...

CAFs interact with mesenchymal glioblastoma stem cells (GSCs) and M2 macrophages, promoting tumor growth via PDGF, TGF-β, osteopontin, and HGF signaling, making them a potential therapeutic target ...

Expert Rev Neurother. 2008;8(10):1457-1473.