Mar. 13, 2025 — A study shows that high-grade glioma tumor cells harboring DNA alterations in the gene PDGFRA responded to the drug avapritinib, which is already approved by the United States ...
CAFs interact with mesenchymal glioblastoma stem cells (GSCs) and M2 macrophages, promoting tumor growth via PDGF, TGF-β, osteopontin, and HGF signaling, making them a potential therapeutic target ...
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