Adding metformin to letrozole and abemaciclib (Verzenio) was tied to deep responses and prolonged progression-free survival (PFS) in some patients with recurrent estrogen receptor (ER)-positive ...

Professor Peter Garland CBE, who served as Chief Executive of the ICR from 1989 to 1999, passed away on 5 March. He also played an important role as the Chair of Cambridge Antibody Technology (CAT) ...

The data suggest that combination therapies with (Z)-endoxifen and agents targeting topoisomerase, CDK, mTOR/PI3K and AKT have potential in the treatment of breast cancer b Insilico and Chemical ...

One of the key players in mediating pro-inflammatory signaling is the Janus Kinase (JAK) 1/2. Signaling via JAK1/2 and signal transducer and activator of transcription (STAT) pathways are crucial for ...

Adenosine is a metabolite, which has long been implicated in a variety of inflammatory processes. Inhaled adenosine provokes bronchoconstriction in asthmatics or chronic obstructive pulmonary disease ...

Isolation and Identification of Compounds from Bioactive Extracts of Taraxacum officinale Weber ex F. H. Wigg. (Dandelion) as a Potential Source of Antibacterial Agents.

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State Key Laboratory of Natural Medicines, Department of Organic Chemistry, China Pharmaceutical University, Nanjing 210009, China ...