A European research collaboration has found that besides regulating the fusion of mitochondria, Mitofusin 2 also ensures protein quality control. This discovery could open up new routes to treating ...

Researchers from Cologne, Bochum, Padova and Angers have discovered a novel connection between mitochondrial function, protein quality control and ...

Mitochondria are critical for cellular homeostasis, regulating bioenergetics, redox balance, Ca2+ signaling, and cell death. Mitochondrial Ca2+ ...

A review by a team of researchers at the Chinese Academy of Science highlights the role of mitochondrial Ca 2+ imbalance in neurodegenerative diseases, including Alzheimer's disease (AD ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

Peptides have emerged as a fascinating class of biomolecules with multifaceted roles across biological systems. Vesugen, a ...

In a variety of diseases, including neurodegenerative disorders and ... During the study, researchers found that mitochondria act as a “reservoir” to hold NAD and supply it to the cell as ...

Scientists at the University of Exeter have identified an unexpected potential contributor to human health and longevity: ...

In the coming years, an unprecedented number of people will leave planet Earth—but it’s becoming increasingly clear that deep ...