Note that vesicle clouds, and therefore synapses, are located primarily in basal regions including neurites. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-56115-2 ...

The human neurons grew multiple neurites, or wiry projections that help the nerve cells send and receive signals. But the chimp neurons only grew single neurites. When human HARs were engineered into ...

RNA localization and localized translation are especially relevant in polarized cells like neurons where neurites extend dozens to hundreds of centimeters away from the soma. Local translation confers ...

The researchers noticed that human nerve cells grow multiple neurites, which are tiny branches that help with communication between cells. Chimpanzee neurons in the same setting grew fewer branches, ...

This fundamental study reports the effects of the psychedelic drug psilocin on iPSC-derived human cortical neurons, analyzing different aspects of structural and functional neuronal plasticity. The ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. An evolutionarily conserved micropeptide, ...

Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States Neuroscience Interdepartmental Program, University of California, Los ...

Version of Record: This is the final version of the article. The authors try to establish that there is an Abeta-dependent loss of nuclear pores early in Alzheimer's disease. To do so the authors ...

The Ca 2+-dependent activator protein for secretion (CAPS/CADPS) family protein facilitates catecholamine release through the dense-core vesicle exocytosis in model neuroendocrine cell lines. However, ...

Inclusions of pathogenic deposits containing TAR DNA-binding protein 43 (TDP-43) are evident in the brain and spinal cord of patients that present across a spectrum of neurodegenerative diseases. For ...