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Researchers used integrated Mendelian randomization in a cohort of over 247,000 individuals to identify 62 plasma proteins associated with breast cancer risk. Nine high-confidence targets, including ...
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including atypical haemolytic uraemic syndrome (AHUS), immune complex membranoproliferative glomerulonephritis (IC-MPGN), and lupus nephritis. Other potential rivals in C3G include Apellis' C3 ...
In this presentation I will review evidence that immune complexes are responsible for the development of glomerulonephritis ... resembles SLE nephritis. At the outset, it is appropriate to comment ...
The REGENCY trial was a randomized, double-blind, placebo-controlled study conducted across 15 countries, involving 271 adults with biopsy-proven active lupus nephritis. Participants were randomly ...
No writing assistance was utilized in the production of this manuscript. Lupus nephritis (LN) is one of the most serious complications of systemic lupus erythematosus. Immunological features ...
The US regulator has started a review of Roche's supplemental biologics license application (BLA) for Gazyva/Gazyvaro (obinutuzumab) as a treatment for lupus nephritis, with a decision expected in ...
Expert Rev of Obstet Gynecol. 2012;7(3):269-279. In summary, excess levels of urobilinogen and bilirubin in the urine may signal liver disease, and more research is needed to correlate these ...
While the emergence of immune checkpoint inhibitors has improved cancer patient outcomes, efficacy in high-grade serous ovarian cancer (HGSOC) is limited. Here, the authors report a phase 2 ...
The following is a summary of “Factors associated with worsening interstitial fibrosis/tubular atrophy in lupus nephritis patients undergoing clinically indicated repeat kidney biopsy,” published in ...