In a significant development for US law enforcement in the battle against cartel-related drug trafficking, Jose Ramon ...

This annual event involved the student body visiting different non-profits around the city Thursday.

The Seward baseball team won their first two games of their west Texas road trip by taking two at Odessa Friday afternoon. The Saints took two from the Odessa Wranglers 4-2 and 9-2.

A Mexican national residing unlawfully in Texas has been sentenced to life in federal prison for leading a drug trafficking ...

Duncanville senior quarterback Keelon Russell was the offensive player of the year on the Blue Bell/Texas Sports Writers ...

A Midland drug trafficker, Jose Ramon Castillo-Lopez, 30 of Namiquipa, Chihuahua, Mexico with ties to a Mexican cartel has ...

The Odessa American is the leading source of local news, information, entertainment and sports for the Permian Basin.

Love elote? We've rounded up the top three places in Odessa serving up this delicious Mexican treat. Check them out!

The leader of a drug trafficking organization that distributed narcotics in Amarillo was sentenced to life in prison Thursday ...