In contrast to the limited number of data points that can be assessed by conventional transcriptional analysis (e.g. with the polymerase chain reaction [PCR]), microarrays provide a genome-wide ...

A role for BRCA1 in the direct and indirect regulation of transcription is well established. However, a comprehensive view of the degree to which BRCA1 impacts transcriptional regulation on a ...

Analysis of the human transcriptome is often limited to annotated sequences. In the May 3 Science, Philipp Kapranov and colleagues at Affymetrix Inc., California provide evidence for many undiscovered ...

Transcriptome Analysis. Compared to microarray-based methods, the paramount advantage of DGE is that the transcripts are counted and “you do not depend on semi-quantitative analysis of light ...

Microarray-based technologies are widely used to monitor cellular changes in ... "Quantitative transcriptome analysis is potentially widely applicable to determine the target proteins and action ...

In 2009, nearly all NIH funding to grants in their first year concerning gene expression went to projects using microarrays, according to an analysis by Dave Delano, senior product manager for gene ...

Microarrays can only detect splicing events during customized conditions, and not during routine use. ... Tissue-Specific Transcriptome Analysis. News-Medical, viewed 14 June 2025, ...

Microarrays also offer simpler data analysis, as it is known ahead of time exactly what kind of data will be returned. With NGS, there’s always the possibility of revealing something new and ...

The resulting analysis gives a snapshot of the transcriptome of the sample, including the identity and abundance of each mRNA. Microarray technology was developed in the 1970s.

(1)Ebeling et al. Genome-based analysis of the nonhuman primate Macaca fascicularis as a model for drug safety assessment. (2011) Genome Research. Published in Advance Aug 23, 2011 . doi:10.1101 ...