Taking into account the previously mentioned benefits, torsemide not furosemide should be the loop diuretic of choice in patients with HF.

Furosemide is the most widely prescribed loop diuretic in the setting of systolic heart failure (HF), yet torsemide has been shown to have less inter- and intra-individual variation in ...

BACKGROUND: Primary aldosteronism (PA), an overt form of renin-independent aldosterone production, leads to a disproportionately high rate of major adverse cardiovascular events (MACEs). Mounting ...

In patients with acute heart failure, the addition of hydrochlorothiazide (HCTZ) to furosemide increased the diuretic response in the CLOROTIC trial (Combining Loop with Thiazide Diuretics for ...

This paper investigates a single degree-of-freedom (DOF) multi-loop-coupled planar continuum morphing mechanism (MPCMM), which can be used in broad application prospects in fields such as robotics, ...

Additionally, SGLT2 inhibitors directly inhibit sodium–hydrogen exchanger 1 (NHE-1), a key regulator of intracellular pH and ion homeostasis. 102,103 SGLT2 inhibitors result in diuresis by a mechanism ...