Our results demonstrate that linear models can be used for meta-analysis of GWAS of binary phenotypes, ... We considered three scenarios for case–control imbalance, described in Table 2, ...

Proper handling of continuous variables is crucial in healthcare research, for example, within regression modelling for descriptive, explanatory, or predictive purposes. However, inadequate methods ...

In these cases, Generalized Linear Models (GLM) are a more appropriate choice for analysis. This short course will introduce the concept, theory, and application of GLM. Moreover, we will discuss some ...

Andreas Buja, Trevor Hastie, Robert Tibshirani, Linear Smoothers and Additive Models, The Annals of Statistics, Vol. 17, No. 2 (Jun., 1989), pp. 453-510. Free online reading for over 10 million ...

Testing a low-dimensional null hypothesis against a high-dimensional alternative in a generalized linear model may lead to a test statistic that is a quadratic form in the residuals under the null ...