Research has shown that small nucleolar RNAs (snoRNAs) play crucial roles in various biological processes, and understanding disease pathogenesis by studying their relationship with diseases is ...

In this letter, the curve linear-linear (CLL) basis functions are extended to higher-order hierarchical linear-linear (HOLL) basis functions. The accuracy of method of moments (MoM) solution for both ...

Generalized additive models (GAM) were applied to model non-linear relationships, and threshold effects were evaluated using two-piece-wise linear regression. Mediation analysis quantified the ...