Entry inhibitors are a class of drugs that block HIV from entering CD4 T cells. These inhibitors include: enfuvirtide (Fuzeon), which belongs to the drug class known as fusion inhibitors maraviroc ...

The chemokine receptors CCR5 and CXCR4 are the two major coreceptors for HIV entry. Numerous efforts have been made to develop a new class of anti-HIV agents that target these coreceptors as an ...

Efavirenz, an HIV drug, shows potential for treating chikungunya virus, inhibiting replication and reducing viral load ...

The global HIV antivirals market is experiencing substantial growth, fueled by rising global awareness, advancements in pharmaceutical research, and the increasing adoption of innovative treatment ...

C-28 modified betulinic acid analogs are potent HIV entry inhibitors, while C-3 modified betulinic acid derivatives function by blocking virus maturation. [127] Among these bevirimat (Figure 23 ...

HIV drugs market is a critical segment of the global pharmaceutical ... transcriptase inhibitors (NNRTIs), protease inhibitors (PIs), integrase inhibitors, and entry inhibitors. The market is ...

Records reviewed by The Intercept show that ICE altered contracts with immigration detention centers to cut transgender care ...

Europe's second-highest court on Wednesday sided with EU antitrust regulators which four years ago penalised UBS , UniCredit ...

In this phase I study, a lentivirus vector was used to deliver three HIV-resistance genes to autologous stem cells: a CCR5 shRNA to block viral entry, a chimeric TRIM5alpha gene to prevent capsid ...

Elevated levels of hs-CRP (P=0.049) and higher IL-6 (P=0.033) at study entry were associated with major cardiovascular events. The study findings suggest that pitavastatin may reduce cardiovascular ...

Responding to the progress of its obesity pipeline, the Chinese biotech is stepping up its investment in metabolic disease ...