Lipid nephrotoxicity could damage the structure and function of the glomerulus and tubules ... proximal convoluted tubules. On the other hand, when GFR increased, the amount of Na+ passing through the ...

Background Proximal muscle rehabilitation is commonly prescribed to address muscle strength and function deficits in individuals with patellofemoral pain (PFP). This review (1) evaluates the efficacy ...

Similarly, cisplatin causes proximal tubular damage that can be relieved by an OCT inhibitor, cimetidine, collectively suggesting the presence of functional OATs and OCTs in organoid proximal tubules ...

This important study addresses the idea that defective lysosomal clearance might be causal to renal dysfunction in cystinosis. With mostly solid data, the authors observe that restoring expression of ...

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Department of Chemistry, Yale University, 225 Prospect Street, New Haven, Connecticut 06520, United States ...