The mathematical form of many optimization problems in engineering is constrained optimization problems. In this paper, an improved genetic algorithm based on two-direction crossover and grouped ...

The paper presents a new dynamic direction restricted algorithm based on the Dijkstra algorithm, direction restricted algorithm and area restricted algorithm for computing shortestpath from one node ...

We present a high-throughput, end-to-end pipeline for organic crystal structure prediction (CSP)─the problem of identifying the stable crystal structures that will form from a given molecule based ...

Protein redesign is an enzyme engineering strategy that enhances a template enzyme’s properties by introducing mutations. Although the method is broadly employed for enzyme design, finding optimal ...