Chemists have developed a protocol to rapidly produce protein chains up to 164 amino acids long. The flow-based technology could speed up drug development and allow scientists to design novel ...

Here we report a fully automated, flow-based approach to solid-phase polypeptide synthesis, with amide bond formation in 7 seconds and total synthesis times of 40 seconds per amino acid residue.

The flow system is 10 to 100 times as fast as batch-based solid-phase peptide synthesis methods currently used, Pentelute says. If the Amidator worked nonstop for a year, it could create tens of ...

Manufacturing small proteins known as peptides is usually very time-consuming, which has slowed development of new peptide drugs for diseases such as cancer, diabetes, and bacterial infections. To ...

Total synthesis of feglymycin based on a linear/convergent hybrid approach using micro-flow amide bond formation. Nat. Commun. 7, 13491 doi: 10.1038/ncomms13491 (2016).