A new ML-guided platform can design thousands of new enzymes, predict how they will behave in the real world, and test their performance.

The researchers explain that this was possible because MaSIF is based on general surface features that apply to proteins and small molecules alike, so they were able to map the small molecule ...

These small molecule-protein complexes can act as precise "on" or "off" switches, modulating cellular processes like DNA transcription ... from MaSIF’s ability to map small molecule features ...

A team at Nagoya University experimented with ways to uncurl a DNA molecule using pressure applied to liquid flowing in a channel, with the pressure flow providing shear force that uncurled the ...

Researchers have previously tried sticking down one end of a DNA molecule to stretch it out, but found that the thermal fluctuations could still cause movement and blurring. "Stretching DNA refers ...

New CABI-led research using publicly-shared DNA barcodes and citizen science images have provided new evidence on the ...

The authors used a combination of super-resolution imaging techniques and liquid pressure flow to fine-tune the stretch ratio of a DNA molecule, improving the lateral resolution of side-by-side ...

A significant advancement in knowledge of the link between cognition and genetics has been made thanks to a study led by ...

a small circular DNA molecule found in bacteria that gets used during vaccine development, according to the National Institutes of Health. Plasmid DNA is essential for manufacturing but must be ...

Once we map these eQTLs to Neandertal-derived DNA variations in a modern human genome, we will be able to infer whether some Neandertal DNA is measurably altering gene expression. A complete ...

Of course, though, testing a child's parentage based on physical features is far too subjective — that's typically where DNA tests come in. Such tests can offer a far more scientific way of ...

Non-crossover maps can probably be refined further by sequencing more DNA samples and using more-sophisticated mathematical modelling. Estimates of the non-crossover rate, how it varies across the ...