SciELO4d
Evaluation of single-dose umbilical cord blood-derived mononuclear cell injection immediately and 7 days after spinal cord trauma in mice
Penetration through most tissue membranes occurs within minutes due to a reversible alteration in protein configuration when DMSO replaces water. 31 This agent is also used as the intracellular ...
Frontiers28d
Comprehensive overview of the toxicities of small-molecule cryoprotectants for carnivorous spermatozoa: foundation for computational cryobiotechnology
For example, SwissADME is known for its ability to predict the absorption, distribution, metabolism, and excretion (ADME) properties, which are crucial for assessing the suitability of a ...
The EMBO Journal8d
Nanoscale analysis of human G1 and metaphase chromatin in situ
Ordered stacked dinucleosomes not detected in glycerol-treated cells and have a different structure in non-cryoprotected cells To determine if glycerol and DMSO treatment lead to differences in ...
C&EN25d
“Allergolds”: Gold Nanocluster-Based Bioconjugates of Food Allergens with Reduced Immunoglobulin E Binding
Allergen-specific immunotherapy represents the only method of achieving a lasting reduction in the severity of allergic symptoms. However, the need to expose patients to the allergens to which they ...
C&EN25d
SI/II Pocket of Ras: An Opportunity for a Once “Undruggable” Target
Laboratory of Molecular Modeling Applied to the Chemical and Biological Defense (LMCBD), Military Institute of Engineering (IME), Praça General Tibúrcio 80, 22290-270 Rio de Janeiro, Brazil Center for ...
Frontiers22d
Optimizing cryopreservation conditions for use of fucosylated human mesenchymal stromal cells in anti-inflammatory/immunomodulatory therapeutics
These solutions were made as follows: 1) saline solution (0.9% NaCl; Braun, Frankfurt, Germany) containing 10% dimethyl sulfoxide (DMSO; CryoSure, WAK-Chemie Medical GmbH, Steinbach, Germany) and 2% ...