Much of the "junk" DNA in Drosophila shows signs of either negative or positive selection, according to a study in this week's Nature. An analysis by Peter Andolfatto of the University of California, ...

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the non ...

For many years, it was easier for scientists to simply ignore all of that extra genetic material, and it was written off as junk DNA that served no purpose. But in recent decades, the importance of ...

The mechanism reveals that damages to non-coding DNA, which are often hidden, accumulate more in slowly proliferating tissues ...

The findings, which highlight the importance of non-coding regions of DNA, have been reported in the New England Journal of Medicine. Only about two percent of the human genome codes for protein, and ...

In a recent review published in Nature, a group of authors reviewed the progress and challenges in annotating the human genome, including protein-coding genes, isoforms, and non-coding ribonucleic ...

Only 2% of human DNA contains the 'code' to produce proteins, key building blocks of life. The remaining 98% is 'non-coding' and was once thought to be unnecessary 'junk' DNA, but there is ...

11 RNAi differs from CRISPR in that RNAi blocks gene expression at the mRNA level, whereas CRISPR blocks gene expression at the DNA level. Another class of small non-coding RNA is Piwi-interacting ...

Sorting through non-coding DNA to find the root of chemotherapy resistance "The non-coding 98% of the genome contains instructions," said co-first author Jackson Mobley, Ph.D., St. Jude Department ...

DNA molecules contain coding regions—the genes that code for proteins—and non-coding regions that are involved in the mechanisms that regulate or organize the genome. Constantly damaged by ...